About Me

Bhoom Suktitipat, MD, PhD

Assistant Professor
Graduate Program in Medical Bioinformatics
Department of Biochemistry
Faculty of Medicine Siriraj Hospital
Mahidol University

Principal Investigator
Integrative Computational BioScience (ICBS) Center
Mahidol University

Professional Summary

Dr.Bhoom Suktitipat graduated with an M.D. from Faculty of Medicine Siriraj Hospital, Mahidol University in 2003. In the same year, he started working as an instructor at the Department of Biochemistry, Faculty of Medicine Siriraj Hospital. He received his Ph.D. in Epidemiology with a focus in Genetic Epidemiology from the Johns Hopkins Bloomberg School of Public Health in 2010, and worked as a postdoctoral fellow in Statistical Genetics at the National Human Genome Research Institute, NIH, from 2010-2012. Dr. Suktitipat’s research focuses on the development and application of statistical methods to understand the effect of important genetic variations and human diseases.

EDUCATION:

1997-2003



2005-2010




2005-2010









2010-2012

MD (First Class Honor)
– Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand

Graduate diploma (Basic Medical Science)
– Faculty of Medicine Siriraj Hospital, Mahidol University, Thailand

PhD, (Epidemiology focused on Genetic Epidemiology),
Bloomberg School of Public Health, the Johns Hopkins University, Baltimore, MD
Thesis Title: Genetic Control of Selected Inflammatory Markers in Families with Early Onset Coronary Artery.
Advisor: Prof. M. Daniele Fallin

Postdoctoral visiting fellow
– Postdoctoral training in statistical genetics with Prof. Alexander F. Wilson
– Genometrics section, Inherited Disease Research Branch, National Human Genome Research Institute, National Institutes of Health, USA

PUBLICATIONS:

Original Peer-Reviewed Papers: >>> Articles in PubMed

  1. Chuenkongkaew WL, Suphavilai R, Vaeusorn L, Phasukkijwatana N, Lertrit P, Suktitipat B. Proportion of 11778 mutant mitochondrial DNA and clinical expression in a thai population with leber hereditary optic neuropathy. J Neuroophthalmol 2005;25(3):173-5. PMID: 16148621. IF=1.628
  2. Phasukkijwatana N, Chuenkongkaew WL, Suphavilai R, Suktitipat B, Pingsuthiwong S, Ruangvaravate N, Atchaneeyasakul LO, Warrasak S, Poonyathalang A, Sura T, Lertrit P. The unique characteristics of Thai Leber hereditary optic neuropathy: analysis of 30 G11778A pedigrees. J Hum Genet 2006;51(4):298-304. PMID: 16477364. IF=2.365
  3. Tharaphan P, Chuenkongkaew WL, Luangtrakool K, Sanpachudayan T, Suktitipat B, Suphavilai R, Srisawat C, Sura T, Lertrit P. Mitochondrial DNA haplogroup distribution in pedigrees of Southeast Asian G11778A Leber hereditary optic neuropathy. J Neuroophthalmol 2006;26(4):264-7. PMID: 17204919. IF=1.628
  4. Chen GK, Zheng T, Witte JS, Goode EL, Gao L, Hu P, Suh YJ, Suktitipat B, Szymczak S, Woo JH, Zhang W. Genome-wide association analyses of expression phenotypes. Genet Epidemiol 2007;31 Suppl 1:S7-S11. PMID: 18046762. IF=4.015
  5. Lertrit P, Poolsuwan S, Thosarat R, Sanpachudayan T, Boonyarit H, Chinpaisal C, Suktitipat B. Genetic history of Southeast Asian populations as revealed by ancient and modern human mitochondrial DNA analysis. Am J Phys Anthropol 2008;137(4):425-40. PMID: 18615504. IF=2.481
  6. Klein AP, Suktitipat B, Duggal P, Lee KE, Klein R, Bailey-Wilson JE, Klein BE. Heritability analysis of spherical equivalent, axial length, corneal curvature, and anterior chamber depth in the Beaver Dam Eye Study. Arch Ophthalmol 2009;127(5):649-55. PMID: 19433716. PMCID: PMC2739587. IF=3.826
  7. Sun H, Swaim A, Herrera JE, Becker D, Becker L, Srivastava K, Thompson LE, Shero MR, Perez-Tamayo A, Suktitipat B, Mathias R, Contractor A, Faraday N, Morrell CN. Platelet kainate receptor signaling promotes thrombosis by stimulating cyclooxygenase activation. Circ Res 2009;105(6):595-603. PMID: 19679838. PMCID: PMC2771168. IF=11.861
  8. Assimes TL, Hólm H, Kathiresan S, Reilly MP, Thorleifsson G, Voight BF, Erdmann J, Willenborg C, Vaidya D, Xie C, Patterson CC, Morgan TM, Burnett MS, Li M, Hlatky MA, Knowles JW, Thompson JR, Absher D, Iribarren C, Go A, Fortmann SP, Sidney S, Risch N, Tang H, Myers RM, Berger K, Stoll M, Shah SH, Thorgeirsson G, Andersen K, Havulinna AS, Herrera JE, Faraday N, Kim Y, Kral BG, Mathias RA, Ruczinski I, Suktitipat B, Wilson AF, Yanek LR, Becker LC, Linsel-Nitschke P, Lieb W, König IR, Hengstenberg C, Fischer M, Stark K, Reinhard W, Winogradow J, Grassl M, Grosshennig A, Preuss M, Schreiber S, Wichmann HE, Meisinger C, Yee J, Friedlander Y, Do R, Meigs JB, Williams G, Nathan DM, MacRae CA, Qu L, Wilensky RL, Matthai WH Jr, Qasim AN, Hakonarson H, Pichard AD, Kent KM, Satler L, Lindsay JM, Waksman R, Knouff CW, Waterworth DM, Walker MC, Mooser VE, Marrugat J, Lucas G, Subirana I, Sala J, Ramos R, Martinelli N, Olivieri O, Trabetti E, Malerba G, Pignatti PF, Guiducci C, Mirel D, Parkin M, Hirschhorn JN, Asselta R, Duga S, Musunuru K, Daly MJ, Purcell S, Eifert S, Braund PS, Wright BJ, Balmforth AJ, Ball SG; Myocardial Infarction Genetics Consortium; Wellcome Trust Case Control Consortium; Cardiogenics, Ouwehand WH, Deloukas P, Scholz M, Cambien F, Huge A, Scheffold T, Salomaa V, Girelli D, Granger CB, Peltonen L, McKeown PP, Altshuler D, Melander O, Devaney JM, Epstein SE, Rader DJ, Elosua R, Engert JC, Anand SS, Hall AS, Ziegler A, O’Donnell CJ, Spertus JA, Siscovick D, Schwartz SM, Becker D, Thorsteinsdottir U, Stefansson K, Schunkert H, Samani NJ, Quertermous T. Lack of association between the Trp719Arg polymorphism in kinesin-like protein 6 and coronary artery disease in 19 case-control studies. J Am Coll Cardiol. 2010;56(19):1552-63. PMID: 20933357. PMCID: PMC3084526. IF: 14.086
  9. Kral BG, Mathias RA, Suktitipat B, Ruczinski I, Vaidya D, Yanek LR, Quyyumi AA, Patel RS, Zafari AM, Vaccarino V, Hauser ER, Kraus WE, Becker LC, Becker DM. A Common variant in the CDKN2B gene on chromosome 9p21 protects against coronoary artery disease in Americans of African ancestry. J Hum Genet. 2011 Mar;56(3):224-9. Epub 2011 Jan 27; doi:10.1038/jhg.2010.171. PMID: 21270820. PMCID: IF: 2.37
  10. Mathias RA, Sergeant S, Ruczinski I, Torgerson DG, Hugenschmidt CE, Kubala M, Vaidya D, Suktitipat B, Ziegler JT, Ivester P, Case D, Yanek LR, Freedman BI, Rudock ME, Barnes KC, Langefeld CD, Becker LC, Bowden DW, Becker DM, Chilton FH. The impact of FADS genetic variants on ω6 polyunsaturated fatty acid metabolism in African Americans. BMC Genet. 2011 May 20;12:50. PMID: 21599946. PMCID: PMC3118962. IF:2.81
  11. Kaewsutthi S, Phasukkijwatana N, Joyjinda Y, Chuenkongkaew W, Kunhapan B, Tun AW, Suktitipat B, Lertrit P. Mitochondrial haplogroup background may influence Southeast Asian G11778A Leber hereditary optic neuropathy. Invest Ophthalmol Vis Sci. 2011 Jul 1;52(7):4742-8. PMID: 21398275. IF:3.43
  12. Faraday N, Yanek LR, Yang XP, Mathias R, Herrera-Galeano JE, Suktitipat B, Qayyum R, Johnson AD, Chen MH, Tofler GH, Ruczinski I, Friedman AD, Gylfason A, Thorsteinsdottir U, Bray PF, O’Donnell CJ, Becker DM, Becker LC. Identification of a specific intronic PEAR1 gene variant associated with greater platelet aggregability and protein expression. Blood. 2011 Sep 22;118(12):3367-75. PMID: 21791418. PMCID: PMC3179402. IF: 9.9
  13. N’diaye A, Chen GK, Palmer CD, Ge B, Tayo B, Mathias RA, Ding J, Nalls MA, Adeyemo A, Adoue V, Ambrosone CB, Atwood L, Bandera EV, Becker LC, Berndt SI, Bernstein L, Blot WJ, Boerwinkle E, Britton A, Casey G, Chanock SJ, Demerath E, Deming SL, Diver WR, Fox C, Harris TB, Hernandez DG, Hu JJ, Ingles SA, John EM, Johnson C, Keating B, Kittles RA, Kolonel LN, Kritchevsky SB, Le Marchand L, Lohman K, Liu J, Millikan RC, Murphy A, Musani S, Neslund-Dudas C, North KE, Nyante S, Ogunniyi A, Ostrander EA, Papanicolaou G, Patel S, Pettaway CA, Press MF, Redline S, Rodriguez-Gil JL, Rotimi C, Rybicki BA, Salako B, Schreiner PJ, Signorello LB, Singleton AB, Stanford JL, Stram AH, Stram DO, Strom SS, Suktitipat B, Thun MJ, Witte JS, Yanek LR, Ziegler RG, Zheng W, Zhu X, Zmuda JM, Zonderman AB, Evans MK, Liu Y, Becker DM, Cooper RS, Pastinen T, Henderson BE, Hirschhorn JN, Lettre G, Haiman CA. Identification, replication, and fine-mapping of Loci associated with adult height in individuals of african ancestry. PLoS Genet. 2011 Oct;7(10):e1002298. Epub 2011 Oct 6. PMID: 21998595. PMCID: PMC3084526. IF: 8.69
  14. Suktitipat B, Mathias RA, Vaidya D, Yanek LR, Young JH, Becker LC, Becker DM, Wilson AF, Fallin MD. The Robustness of Generalized Estimating Equations for Association Tests in Extended Family Data. Hum Hered. 2012; 74: 17-26. PMID: 23038411. IF: 1.79
  15. Kim Y, Suktitipat B, Yanek LR, Faraday N, Wilson AF, Becker DM, Becker LC, Mathias RA. Targeted deep resequencing identifies coding variants in the PEAR1 gene that play a role in platelet aggregation. PLoS One. 2013 May 21;8(5):e64179. doi: 10.1371/journal.pone.0064179. PMID: 23704978. IF: 3.73
  16. Sattayasai J, Chaonapan P, Arkaravichie T, Soi-Ampornkul R, Junnu S, Charoensilp P, Samer J, Jantaravinid J, Masaratana P,Suktitipat B, Manissorn J, Thongboonkerd V, Neungton N, Moongkarndi P. Protective Effects of Mangosteen Extract on H2O2-Induced Cytotoxicity in SK-N-SH Cells and Scopolamine-Induced Memory Impairment in Mice. PLoS One. 2013 Dec 27;8(12):e85053. doi: 10.1371/journal.pone.0085053. IF 3.73
  17. Opasanon S, Pongsapich W, Taweepraditpol S, Suktitipat B, Chuangsuwanich A. Clinical Effectiveness of Hyperbaric Oxygen Therapy in Complex Wounds. J Am Coll Clin Wound Spec. 2015 Apr 9;6(1-2):9-13. doi: 10.1016/j.jccw.2015.03.003. eCollection 2014 Apr. PMID: 26442206.
  18. Suktitipat B, Naktang C, Mhuantong W, Tularak T, Artiwet P, Pasomsap E, Jongjaroenprasert W, Fuchareon S, Mahasirimongkol S, Chantratita W, Yimwadsana B, Charoensawan V, Jinawath N. Copy Number Variation in Thai Population. PLoS One. 2014 Aug 13;9(8):e104355. doi: 10.1371/journal.pone.0104355. IF 3.53
  19. Jirawatnotai S, Sharma S, Michowski W, Suktitipat B, Geng Y, Quackenbush J, et al. The cyclin D1-CDK4 oncogenic interactome enables identification of potential novel oncogenes and clinical prognosis. Cell Cycle. 2014;13(18):2889-900. doi: 10.4161/15384101.2014.946850. IF 5.01
  20. Tresukosol D, Suktitipat B, Hunnangkul S, Kamkaew R, Poldee S, Tassaneetrithep B, and Likidlilid A. Effects of Cytochrome P450 2C19 and Paraoxonase 1 Polymorphisms on Antiplatelet Response to Clopidogrel Therapy in Patients with Coronary Artery Disease. PLoS ONE. 2014 Oct 16; 9(10): e110188. doi:10.1371/journal.pone.0110188. IF 3.53
  21. Li Q, Kim Y, Suktitipat B, Hetmanski JB, Marazita ML, Duggal P, Beaty TH, Bailey-Wilson JE. Gene-Gene Interaction Among WNT Genes for Oral Cleft in Trios. Genet Epidemiol. 2015 Feb 6. doi: 10.1002/gepi.21888. PMID: 25663376. IF:951
  22. Pithukpakorn M, Roothumnong E, Angkasekwinai N, Suktitipat B, Assawamakin A, Luangwedchakarn V, Umrod P, Thongnoppakhun W, Foongladda S, Suputtamongkol Y. HLA-DRB1 and HLA-DQB1 Are Associated with Adult-Onset Immunodeficiency with Acquired Anti-Interferon-Gamma Autoantibodies. PLoS One. 2015 May 26;10(5):e0128481. doi: 10.1371/journal.pone.0128481. eCollection 2015. PMID: 26011559. IF: 3.53
  23. Qayyum R, Becker LC, Becker DM, Faraday N, Yanek LR, Leal SM, Shaw C, Mathias R, Suktitipat B, Bray PF. Genome-wide association study of platelet aggregation in African Americans. BMC Genet. 2015 May 30;16(1):58. doi: 10.1186/s12863-015-0217-9.PMID: 26024889. IF 2.40
  24. Phoompoung P, Ankasekwinai N, Pithukpakorn M, Foongladda S, Umrod P, Suktitipat B, Mahasirimongkol S, Kiertiburanakul S, Suputtamongkol Y. Factors associated with acquired Anti IFN- γ autoantibody in patients with nontuberculous mycobacterial infection. PLoS One. 2017 Apr 24;12(4):e0176342. doi: 10.1371/journal.pone.0176342. eCollection 2017. PMID: 28437431. IF: 2.82
  25. SuktitipatB, Sathirareuangchai S, Roothumnong E, Thongnoppakhun W, Wangkiratikant P, Vorasan N, Krittayaphong R, Pithukpakorn M, Boonyapisit W. Molecular investigation by whole exome sequencing revealed a high proportion of pathogenic variants among Thai victims of sudden unexpected death syndrome. PLoS One. 2017 Jul 13;12(7):e0180056. doi: 10.1371/journal.pone.0180056. eCollection 2017. PMID: 28704380. IF: 2.82
  26. Lert-Itthiporn W, Suktitipat B, Grove H, Sakuntabhai A, Malasit P, Tangthawornchaikul N, Matsuda F, Suriyaphol P.Validation of genotype imputation in Southeast Asian populations and the effect of single nucleotide polymorphism annotation on imputation outcome.BMC Med Genet. 2018 Feb 13;19(1):23. doi: 10.1186/s12881-018-0534-8. PMID: 29439659. IF: 1.91

Other Publications:

  1. Suktitipat B. Genetic Control of Selected Inflammatory Markers in Families with Early Onset Coronary Artery.  [Ph.D. Dissertation].  Baltimore, Maryland: the Johns Hopkins University, 2010. 159p.
  2. Sriampornkul R, Junnu S, Chotinaiwattarakul W, Wongmanee U, Suktitipat B, Neungton N. Comparative analysis of serum ceruloplasmin levels in Wilson Disease by conventional enzymatic assay and immunologic method. Siriraj Med J 2006;58:600-5.
  3. Jinawath N, Suktitipat B. Application of next-generation sequencing technology in the diagnosis, treatment, and cancer research. Thai J. Genet. 2013, S(1): 62-65. (Article in Thai)
  4. Suktitipat B, Peerapittayamongkol C. What have we learned from the past 7 years and the millions of dollars spent on the genome-wide association studies? Bangkok Med J, 2014;7:99-101.

Book/Book chapters:

  1. มานพ พิทักษ์ภากร, ศิวนนท์ จิรวัฒโนทัย,​ ภูมิ สุขธิติพัฒน์. หลักการของอณูพันธุศาสตร์และพันธุศาสตร์ของมะเร็ง. กรุงเทพ: สำนักพิมพ์คณะแพทยศาสตร์ศิริราชพยาบาล; 2559. 285p.
    • ภูมิ สุขธิติพัฒน์. ประชากรพันธุศาสตร์. หลักการของอณูพันธุศาสตร์และพันธุศาสตร์ของมะเร็ง. กรุงเทพ: สำนักพิมพ์คณะแพทยศาสตร์ศิริราชพยาบาล; 2559. p.41-56.
    • ภูมิ สุขธิติพัฒน์. โรคพันธุกรรมแบบพหุปัจจัย. หลักการของอณูพันธุศาสตร์และพันธุศาสตร์ของมะเร็ง. กรุงเทพ: สำนักพิมพ์คณะแพทยศาสตร์ศิริราชพยาบาล; 2559. p.57-66.

Office Address:

Srisavarindira Bld, Fl.10
2 Wanglang Road,
Bangkoknoi, Bangkok Thailand 10700
Telephone: (+66) 02-419-9146
FAX: (+66) 02-419-9141
E-mail: bhoom.suk[#]mahidol.edu

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